But while the Premier League will miss his terrific goals and temper tantrums, it seems the blue half of Manchester will miss the man himself even more, having taken Super Mario to their hearts.
It's a shame, because this Man About Town seems to be right at home and knows all the Mancunian landmarks, from the cobbles of Coronation Street to the Castlefield canals.
To mark the launch of the Ballotelli bobblehead figurine, out just in time to be the perfect Christmas stocking filler for any young (or old) City fan, mini Mario's been on a little tour.
He's been spotted outside the Rovers Return, the famous pub in ITV soap Coronation Street, on the Lowry bridge in the city centre and grabbing a bite to eat at San Carlo, the award-winning restaurant.
And his 'Why Always Me?' t-shirt was appropriate when forced into battle with some Daleks at the Museum of Science and Industry.
Rovers return: Balotelli boblehead on the famous cobbles of Coronation Street
Read all about it: Balotelli waits outside Corrie's famous corner shop The Kabin
Neighbourhood watch: Balotelli seems to be waiting for a kickabout with Kev Webster
The real Balotelli found it hilarious when he came face-to-face with his plastic alter ego at the club's Carrington training ground this week.
No doubt he's added it to his Christmas wish list.
Bobbleheads seem to be enjoying a surge in popularity this year, with the City figurines hot on the heels of a West Ham collection featuring owners David Gold and David Sullivan, and Hammers star Mark Noble.
Bite to eat: Balotelli pops into his favourite restaurant San Carlo
Road block: Balotelli posing alongside his favoured Bentley Continental GT
Love story: Balotelli once scribed the word City
onto a promotional 'I love Manchester' warm-up t-shirt he wore at the
Etihad Stadium